In a dystopian future, the Earth's atmosphere is rendered toxic and most of the population has fled the planet and colonised one of Jupiter's moons, Io. Sam (Margaret Qualley), one of the last survivors on Earth, is a young scientist dedicated to finding a way for humans to adapt and survive, rather than abandon their world. But with the final shuttle scheduled to leave the planet for a distant colony, her determination to stay is rocked by the arrival of Micah (Anthony Mackie), who is racing to catch the last shuttle off the planet. Sam must decide whether to journey with him to join the rest of humanity and begin life anew, or stay to fight for Earth's survival.
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