By turns fiery and funny, this offbeat saga revolves around Mike Howell, a drug addict who spends most of his time writing graphic novels and works as a convenience store clerk. He lives in a small town with his long-term live-in girlfriend, Phoebe Larson, whom he is planning to propose to.
When his life is threatened out of the blue, he finds that he has extraordinary skills in defending himself and killing others. He also begins to question the fact that he has no memory of his life before he came to live in the town. Although he has no memory of it, it turns out that Mike is actually a member of the CIA and trained to be a lethal killing machine.
When the agency targets him for termination, his former handler activates his latent skills, turning the mild-mannered slacker into a deadly weapon. Now, the utterly surprised Mike must use his new-found abilities to save himself and his girlfriend from the dangers of a deadly government operation they find themselves embroiled in.